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New technique may better detect cystic fibrosis in newborns


Researchers have identified new biological markers of cystic fibrosis (CF), a genetic disease which affects children and young adults, leaving them with lifelong health complications including digestive problems and persistent lung infections.

The findings, published in the journal ACS Central Science, shed new light on the underlying mechanisms of CF. They may could lead to improved prognosis and better therapies for a disease which is quite variable, affecting different children in different ways, say researchers.

“There are chemical signatures in sweat that tell us an infant has CF even when they do not exhibit any symptoms,” says Philip Britz-McKibbin, lead author of the study and a professor in the Department of Chemistry & Chemical Biology at McMaster University. “We set out to discover whether there were chemical indicators detected in sweat that could complement the gold standard for CF diagnosis: the sweat chloride test.”


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McMaster University - Faculty of Science

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Office of the Dean of Science
McMaster University
Burke Science Building (BSB), Room 102
1280 Main Street West
Hamilton, Ontario, Canada
L8S 4K1

Contact Information

Business Hours:
8:30AM - 12:00PM + 1:00PM - 4:30PM
Telephone Inquiries:
+1 (905) 525-9140 ext.22616
Fax:
(905) 546-9995
Student Inquiries:
science@mcmaster.ca

McMaster University - Faculty of Science

Mailing Address

Office of the Dean of Science
McMaster University
Burke Science Building (BSB), Room 102
1280 Main Street West
Hamilton, Ontario, Canada
L8S 4K1

Contact Information

Business Hours:
8:30AM - 12:00PM + 1:00PM - 4:30PM
Telephone Inquiries:
+1 (905) 525-9140 ext.22616
Fax:
(905) 546-9995
Student Inquiries:
science@mcmaster.ca