Integrative Neuromuscular Biology Laboratory

Integrative Neuromuscular Biology Laboratoy

The focus of the research in the Integrative Neuromuscular Biology Laboratoy is to investigate molecular mechanisms of neuromuscular plasticity, with an emphasis on identifying new therapeutic strategies for neuromuscular disorders.
The central experimental questions that form the foundation of our research program are:

  1. What roles do phenotype-modifying proteins play in the maintenance and remodeling of the peripheral neuromuscular system, and
  2. Are these molecules efficacious therapeutic targets for inherited and acquired neuromuscular disorders?

To address these questions, we design investigations around lifestyle- and pharmacological-based strategies focused on the manipulation of powerful phenotype-bending molecules in the neuromuscular system. Furthermore, we employ an integrative and rigorous cell-to-animal experimental approach, as well as an innovative combination of molecular physiological solutions. A goal of our research is to decipher how interventions such as physical activity, experimental small molecules, and common generic medications can be used to slow, prevent, or reverse neuromuscular pathologies.

Undergraduate Student Research Opportunities

Undergraduate students interested in thesis, research practicum, or volunteer opportunities within the Integrative Neuromuscular Biology Lab (INBL) are invited to apply by sending an email to the following INBL MS Teams address:

Applications are considered complete if the email contains responses that address the following:

What is your McMaster Student Number?

What is your McMaster email address?

What is your current year of study?

What program are you in?

What lab opportunity are you interested in applying for, i.e., volunteer, research practicum, or thesis?

What semester(s) are you interested in performing the placement, i.e., fall, winter, spring/summer, no preference?

Why are you interested in a research opportunity in the INBL? (150-200 words)

Please discuss any lived experiences that you believe make you a suitable candidate for this opportunity. (150-200 words)

Please list any relevant cell biology, molecular medicine, exercise physiology, statistics, and research methodology courses you have taken.

Please attach an up-to-date copy of your McMaster transcripts.

Applications will be reviewed by Dr. Ljubicic and the INBL research team, who will contact applicants via email for interviews.

We especially welcome applications from First Nations, Métis and Inuit peoples, members of racialized communities (“visible minorities”), persons with disabilities, women, and persons who identify as 2SLGBTQ+

Department of Kinesiology | McMaster University has 1 registered member
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Associate Professor; Canada Research Chair (Tier 2) in Neuromuscular Plasticity in Health and Disease
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Research Interests:

Neuromuscular exercise biology; Duchenne muscular dystrophy; Spinal muscular atrophy; Myotonic dystrophy type 1; Sarcopenia of aging; AMP-activated protein kinase; Protein arginine methyltransferases

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McMaster University - Faculty of Science | Kinesiology